PTI-1: novel way to oncogenicity
نویسندگان
چکیده
منابع مشابه
The Exceptional Oncogenicity of HTLV-1
Human T-cell leukemia virus-1 (HTLV-1) is the first pathogenic human retrovirus identified in 1979 by the Gallo group. HTLV-1 causes fatal T-cell leukemia (adult T cell leukemia) and a progressive myelopahy (HTLV-1-associated myelopathy/ tropical spastic paraparesis, HAM/TSP) and other disorders. Since the discovery of HTLV-1, several other microorganisms are demonstrated to cause cancer in hum...
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Binding a critical pentapeptide region on the scaffolding protein filamin A regulates signaling of mu opioid receptors (MORs) so that their activation should not result in the opioid tolerance, dependence and addiction associated with current opioid painkillers. Additionally, we show that compounds that bind this site on filamin A reduce release of inflammatory cytokines. PTI-609 is a new chemi...
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ژورنال
عنوان ژورنال: Biopolymers and Cell
سال: 2012
ISSN: 0233-7657,1993-6842
DOI: 10.7124/bc.00006c